Suzuki Maki, Hirayama Kazumi
Department of Behavioral Neurology and Neuropsychiatry, Osaka University United Graduate School of Child Development.
Brain Nerve. 2018 Jul;70(7):771-782. doi: 10.11477/mf.1416201078.
It has been proposed that there are two distinct neural circuits underlying human episodic memory. A first circuit connects the hippocampus to the anterior nucleus of the thalamus (hippocampal-anterior thalamic memory circuit). A second circuit conveys fibers from the perirhinal cortex to the dorsomedial nucleus of the thalamus (perirhinal-medial dorsal thalamic memory circuit). In this article, we briefly review research investigating the functional roles of the two circuits in memory, including neuropsychological studies of amnesic patients with thalamic infarcts and functional magnetic resonance imaging (fMRI) studies of healthy participants. On the basis of the findings, we discuss the relationship between thalamic structures, episodic memory, and its disorders (thalamic amnesia).
有人提出，人类情景记忆背后存在两种不同的神经回路。第一种回路将海马体与丘脑前核相连（海马体-丘脑前核记忆回路）。第二种回路将纤维从嗅周皮质传递至丘脑背内侧核（嗅周-丘脑背内侧核记忆回路）。在本文中，我们简要回顾了关于这两种回路在记忆中的功能作用的研究，包括对丘脑梗死失忆患者的神经心理学研究以及对健康参与者的功能磁共振成像（fMRI）研究。基于这些发现，我们讨论丘脑结构、情景记忆及其障碍（丘脑性失忆）之间的关系。
