Huang Zhe, Yang Mingpeng, You Hui, Xie Yang
Institute of Intelligent Machines, Chinese Academy of Sciences.
Department of Instruments Science and Engineering, University of Science and Technology of China.
Anal Sci. 2018;34(7):801-805. doi: 10.2116/analsci.18P022.
A new and simple method for the simultaneous determination of cations and anions by microchip electrophoresis with capacitively coupled contactless conductivity detection (ME-CD) is described. The best analytical performance was found by applying a sinusoidal wave with 800 kHz frequency and 20 V amplitude. An optimized background electrolyte (BGE) composed of 20 mM His/MES and 0.01 mM CTAB was chosen for the simultaneous analysis. Samples containing K, Na, and Li as the cations and Cl, F and PO as anions were analyzed simultaneously in a single run (within 3 min). The reproducibility obtained by the method was compared with those obtained in previous studies that had employed simultaneous analysis of anions and cations by ME-CD. The proposed simultaneous determination method is inexpensive, simple, fast, easy to operate, and offers a high degree of integration.
