Fujiwara Hideyo
J Clin Exp Hematop. 2018;58(2):45-50. doi: 10.3960/jslrt.18006.
In 2017, the revised World Health Organization was published. Regarding myeloproliferative neoplasms, histological findings of bone marrow biopsy is becoming more important for diagnosis. This article highlights particularly the morphology of megakaryocytes and evaluation of myelofibrosis for pathological diagnosis, and immunohistochemistry which can detect somatic mutation.
2017年,世界卫生组织修订版发布。关于骨髓增殖性肿瘤,骨髓活检的组织学检查结果对诊断愈发重要。本文特别强调巨核细胞的形态学以及用于病理诊断的骨髓纤维化评估,还有能够检测体细胞突变的免疫组织化学。