Abstract
No information is available on the clinical use of itraconazole during breastfeeding. However, limited data indicate that maternal itraconazole produces levels in milk that are less than the 5 mg/kg daily doses that have been recommended to treat infants. Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. If itraconazole is used during breastfeeding, monitoring of the infant’s liver enzymes should be considered, especially with long courses of therapy.
摘要
关于母乳喂养期间使用伊曲康唑的临床情况尚无可用信息。然而，有限的数据表明，母亲服用伊曲康唑后，乳汁中的药物水平低于推荐用于治疗婴儿的每日5毫克/千克剂量。在获得更多数据之前，可能更倾向于使用替代药物，尤其是在哺育新生儿或早产儿期间。如果在母乳喂养期间使用伊曲康唑，应考虑监测婴儿的肝酶，尤其是在长期治疗时。
Zotero 插件