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Deferoxamine

Abstract

Deferoxamine is poorly absorbed orally, so it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants.[1] Limited information indicates that maternal doses of deferoxamine up to 2 grams daily do not affect iron levels in breastmilk and did not cause any adverse effects in two breastfed infants.[2] Some experts advocate breastfeeding in women receiving deferoxamine for iron overload caused by beta-thalassemia.[3] However, since little published information is available on the use of deferoxamine during breastfeeding, monitoring of the infant's serum iron is recommended.

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Cochrane Database Syst Rev. 2017 Aug 15;8(8):CD007476. doi: 10.1002/14651858.CD007476.pub3.

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