The effects of maternal alcohol (ethanol) ingestion during lactation are complex and depend on the pattern of maternal drinking. With casual alcohol use (such as 1 glass of wine or beer) it is best to wait 2 to 2.5 hours per drink before nursing. Alcohol can decrease milk production, with 5 drinks or more decreasing milk letdown and disrupting nursing until maternal alcohol levels decrease. Casual drinking does not appear to affect breastfeeding duration, but daily heavy use of alcohol (more than 2 drinks daily) might decrease the length of time that mothers breastfeed their infants. Women with a family history of alcoholism have a blunted prolactin response following breast stimulation and may breastfeed more frequently to compensate. Beer may increase serum prolactin levels during nursing because of polysaccharides from barley and hops. In a US survey of 102 mothers who used beer as a galactogogue, 42% thought it increased milk supply.[1] Although they may contain small amounts of alcohol, nonalcoholic cocktails and beer have minimal risks of infant alcohol exposure via breastmilk when consumed in moderation.[2] The use of alcohol-based hand sanitizers do not result in clinically relevant alcohol levels in breastmilk.[3] Breastmilk alcohol levels closely parallel blood alcohol levels. The highest alcohol levels in milk occur 30 to 60 minutes after an alcoholic beverage, but food delays the time of peak milk alcohol levels. Nursing after 1 or 2 drinks (including beer) can decrease the infant’s milk intake by 20 to 23% and cause infant agitation and poor sleep patterns. Nursing or pumping within 1 hour before ingesting alcohol may slightly reduce the subsequent amounts of alcohol in breastmilk. The long-term effects of daily use of alcohol on infant development are unclear.[4] In infants who were subjected to high alcohol exposure during pregnancy, breastfeeding for 4 or more months markedly improved their scores on the Bayley scales of mental and psychomotor development compared to infants who were breastfed 3 months or less.[5] Heavy maternal use may cause excessive sedation, fluid retention, and hormone imbalances in breastfed infants. Greater or riskier alcohol consumption by nursing mothers may affect their children’s academic performance negatively in school. Preliminary data failed to find an increased risk of autism spectrum disorder or attention deficit hyperactivity disorder among the infants whose mothers used alcohol during breastfeeding.[6]
哺乳期母亲摄入酒精(乙醇)的影响较为复杂,且取决于母亲饮酒的模式。偶尔饮酒(如一杯葡萄酒或啤酒)时,每次饮酒后最好等待2至2.5小时再进行哺乳。酒精会减少乳汁分泌,饮用5杯及以上会减少乳汁排出并干扰哺乳,直至母亲体内酒精水平下降。偶尔饮酒似乎不会影响母乳喂养的持续时间,但每日大量饮酒(每天超过2杯)可能会缩短母亲母乳喂养婴儿的时间。有酗酒家族史的女性在乳房受刺激后催乳素反应迟钝,可能会更频繁地哺乳以作补偿。由于大麦和啤酒花中的多糖,啤酒可能会在哺乳期间提高血清催乳素水平。在美国一项针对102名使用啤酒作为催乳剂的母亲的调查中,42%的人认为啤酒增加了乳汁分泌量。[1] 尽管它们可能含有少量酒精,但适量饮用无酒精鸡尾酒和啤酒时,通过母乳使婴儿接触酒精的风险极小。[2] 使用含酒精的洗手液不会导致母乳中出现具有临床意义的酒精水平。[3] 母乳中的酒精水平与血液中的酒精水平密切相关。饮用酒精饮料后30至60分钟,母乳中的酒精水平最高,但食物会延迟母乳中酒精水平达到峰值的时间。饮用1或2杯(包括啤酒)后进行哺乳会使婴儿的乳汁摄入量减少20%至23%,并导致婴儿烦躁不安和睡眠模式不佳。在摄入酒精前1小时内进行哺乳或挤奶可能会略微减少随后母乳中的酒精含量。每日饮酒对婴儿发育的长期影响尚不清楚。[4] 与母乳喂养3个月或更短时间的婴儿相比,在孕期接触大量酒精的婴儿,母乳喂养4个月或更长时间能显著提高他们在贝利智力和心理运动发育量表上的得分。[5] 母亲大量饮酒可能会导致母乳喂养的婴儿过度嗜睡、液体潴留和激素失衡。哺乳期母亲饮酒量更大或风险更高可能会对其子女在学校的学业成绩产生负面影响。初步数据未能发现母亲在母乳喂养期间饮酒的婴儿患自闭症谱系障碍或注意力缺陷多动障碍的风险增加。[6]