No information is available on the clinical use of vemurafenib during breastfeeding. Because vemurafenib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is 57 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during vemurafenib therapy and for 2 weeks after the final dose.
关于维莫非尼在母乳喂养期间的临床应用尚无可用信息。由于维莫非尼与血浆蛋白的结合率超过99%，其在乳汁中的含量可能较低。然而，其半衰期为57小时，可能会在婴儿体内蓄积。制造商建议在维莫非尼治疗期间及最后一剂后2周内停止母乳喂养。
