No information is available on the clinical use of vandetanib during breastfeeding. Because vandetanib is 90% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is 19 days and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during vandetanib therapy and for 4 months after the last dose.
关于凡德他尼在母乳喂养期间的临床应用尚无可用信息。由于凡德他尼与血浆蛋白的结合率为90%，乳汁中的含量可能较低。然而，其半衰期为19天，可能会在婴儿体内蓄积。制造商建议在凡德他尼治疗期间及最后一剂后4个月内停止母乳喂养。
