Phenindamine is not marketed in the United States. Small occasional doses of phenindamine would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause drowsiness and other effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. The nonsedating antihistamines are preferred alternatives.
非尼拉敏在美国未上市。偶尔小剂量使用非尼拉敏预计不会对母乳喂养的婴儿造成任何不良反应。较大剂量或更长时间使用可能会导致婴儿嗜睡及其他影响，或减少乳汁分泌，尤其是与拟交感神经药如伪麻黄碱联合使用时，或在哺乳期尚未完全建立之前。非镇静性抗组胺药是更合适的替代药物。
