Tolbutamide is no longer marketed in the United States. It is excreted into breastmilk in small amounts that should cause no harm to the breastfed infant. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with hypoglycemic agents.[1,2]
甲苯磺丁脲在美国已不再上市。它会少量排泄到母乳中，应该不会对母乳喂养的婴儿造成伤害。监测母乳喂养婴儿是否有低血糖迹象，如烦躁不安、过度嗜睡、喂养困难、惊厥、发绀、呼吸暂停或体温过低。如果存在担忧，在母亲使用降糖药物治疗期间，建议监测母乳喂养婴儿的血糖。[1,2]
