奥曲肽

Octreotide

Abstract

The excretion of octreotide into breastmilk has not been studied. However, because it has a high molecular weight of 1019 daltons it is likely to be poorly excreted into breastmilk. It is poorly absorbed orally and has been safely administered directly to infants by injection, so it is unlikely to adversely affect the breastfed infant.[1] At least 3 infants have been successfully breastfed with no adverse effects reported. Until more data are available, octreotide should be used in nursing mothers with careful infant monitoring, especially if the infant is under 2 months of age.

摘要

尚未对奥曲肽在母乳中的排泄情况进行研究。然而，由于其分子量高达1019道尔顿，它可能很难排泄到母乳中。它口服吸收差，已通过注射直接安全地给予婴儿，因此不太可能对母乳喂养的婴儿产生不利影响。[1] 至少有3名婴儿成功进行母乳喂养且未报告有不良反应。在获得更多数据之前，奥曲肽应用于哺乳期母亲时应仔细监测婴儿情况，尤其是婴儿年龄在2个月以下时。