Desonide has not been studied during breastfeeding. Since only extensive application of the most potent corticosteroids may cause systemic effects in the mother, it is unlikely that short-term application of topical corticosteroids would pose a risk to the breastfed infant by passage into breastmilk. However, it would be prudent to use the least potent drug on the smallest area of skin possible. It is particularly important to ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1] Desonide cream or foam are acceptable to use on the nipple.[2] Any topical corticosteroid should be wiped off thoroughly prior to nursing if it is being applied to the breast or nipple area.
哺乳期尚未对地奈德进行研究。由于只有广泛应用强效皮质类固醇才可能在母亲体内产生全身作用,短期局部应用皮质类固醇不太可能通过进入母乳而对母乳喂养的婴儿构成风险。然而,尽可能在最小面积的皮肤上使用效力最低的药物是谨慎之举。确保婴儿皮肤不直接接触已治疗的皮肤区域尤为重要。仅应将与水可混溶的乳膏或凝胶产品涂于乳房,因为软膏可能会使婴儿通过舔舐接触到高剂量的矿物石蜡。[1] 地奈德乳膏或泡沫可用于乳头。[2] 如果将任何局部皮质类固醇应用于乳房或乳头区域,在哺乳前应彻底擦拭干净。