Topical diflorasone has not been studied during breastfeeding. Since only extensive application of the most potent corticosteroids may cause systemic effects in the mother, it is unlikely that short-term application of topical corticosteroids would pose a risk to the breastfed infant by passage into breastmilk. However, it would be prudent to use the least potent drug on the smallest area of skin possible. It is particularly important to ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only the lower potency corticosteroids should be used on the nipple or areola where the infant could directly ingest the drugs from the skin; diflorasone should be avoided on the nipple.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2] Any topical corticosteroid should be wiped off thoroughly prior to nursing if it is being applied to the breast or nipple area.
外用双氟拉松在哺乳期的安全性尚未得到研究。由于只有广泛应用最强效的皮质类固醇才可能在母亲体内产生全身作用，因此短期外用皮质类固醇不太可能通过进入母乳而对母乳喂养的婴儿构成风险。然而，尽可能在最小面积的皮肤上使用最低效的药物是谨慎的做法。确保婴儿皮肤不直接接触已治疗的皮肤区域尤为重要。仅应在乳头或乳晕使用低效皮质类固醇，因为婴儿可能会直接从皮肤上摄入药物；应避免在乳头使用双氟拉松。[1] 仅应将水溶性乳膏或凝胶产品涂抹于乳房，因为软膏可能会使婴儿通过舔舐接触到高浓度的矿物石蜡。[2] 如果将任何外用皮质类固醇涂抹于乳房或乳头区域，在哺乳前应彻底擦拭干净。
