Beck H G, Lechner W, Wünsch P H
Z Hautkr. 1985 Nov 1;60(21):1702-4, 1707-10, 1713.
A 86-year-old female patient presented with a ca. walnut-sized, centrally ulcerated preauricular tumor on the right side as well as a firm submandibular lymph node. Histology disclosed a soft-tissue tumor breaking into the lymph node consisting partly of fibroblast-like and partly of histiocyte-like cells. Clinical and histological criteria speak for both an atypical fibroxanthoma (AFX) as well as a malignant fibrous histiocytoma (MFH). A differentiation into two entities does not appear appropriate in our opinion. As the term "AFX" is classified as a benign tumor, "metastasizing AFX" (mAFX) should be considered a special form of MFH or be diagnosed as such, respectively.
一名86岁女性患者右侧出现一个约核桃大小、中央溃疡的耳前肿瘤以及一个坚硬的颌下淋巴结。组织学检查显示为一个侵犯淋巴结的软组织肿瘤,部分由成纤维细胞样细胞组成,部分由组织细胞样细胞组成。临床和组织学标准表明该肿瘤既符合非典型纤维黄色瘤(AFX),也符合恶性纤维组织细胞瘤(MFH)。我们认为将其区分为两种不同实体似乎并不合适。由于“AFX”一词被归类为良性肿瘤,“转移性AFX”(mAFX)应被视为MFH的一种特殊形式,或分别以此进行诊断。