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花生过敏:观念的转变以及过去、现在和未来的方向

Peanut Allergy: Changes in Dogma and Past, Present, and Future Directions.

作者信息

Boudreau-Romano Sarah, Qamar Nashmia

出版信息

Pediatr Ann. 2018 Jul 1;47(7):e300-e304. doi: 10.3928/19382359-20180621-02.

Abstract

The prevalence of food allergy in the pediatric population, specifically to peanuts, has been rising. Accidental exposure to peanuts in a person who is allergic may have life-threatening consequences. Previous recommendations regarding peanut allergy included a delay in introduction of peanut to infants. However, more recent studies have provided sufficient contrary evidence supporting early introduction of peanuts for prevention of peanut allergy. Therefore, prompt evaluation by a specialist should be considered in infants at high risk of developing peanut allergy. Current treatment is strict avoidance of the allergen; however, future therapies are being sought, including oral immunotherapy, sublingual immunotherapy, and epicutaneous immunotherapy. [Pediatr Ann. 2018;47(7):e300-e304.].

摘要

食物过敏在儿科人群中,尤其是对花生过敏的发生率一直在上升。过敏者意外接触花生可能会产生危及生命的后果。以前关于花生过敏的建议包括延迟给婴儿引入花生。然而,最近的研究提供了足够的相反证据,支持早期引入花生以预防花生过敏。因此,对于有发生花生过敏高风险的婴儿,应考虑由专科医生进行及时评估。目前的治疗方法是严格避免接触过敏原;然而,正在寻求未来的治疗方法,包括口服免疫疗法、舌下免疫疗法和经皮免疫疗法。[《儿科年鉴》。2018年;47(7):e300 - e304。]

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