Can Fam Physician. 2018 Jul;64(7):509-513.
At the time of implementation of human papillomavirus (HPV) vaccine immunization programs, concerns were raised by parents, clinicians, and public health professionals about HPV vaccination possibly leading to riskier sexual health choices among young females. If HPV vaccination influences sexual behaviour among vaccinated females, this might influence the effect of HPV vaccination programs. What is known about the effects of the HPV vaccination program on sexual behaviour among young females? Human papillomavirus vaccination has not been associated with increased sexual risk behaviour among young females. However, currently available studies have some important limitations, and future studies should focus on a longitudinal design that includes a prevaccination baseline measurement, adjustment for possible confounders, and measurement of both clinical indicators and behavioural outcomes.
在实施人乳头瘤病毒（HPV）疫苗免疫计划时，家长、临床医生和公共卫生专业人员对 HPV 疫苗接种可能导致年轻女性更危险的性行为提出了担忧。如果 HPV 疫苗接种会影响接种女性的性行为，这可能会影响 HPV 疫苗接种计划的效果。关于 HPV 疫苗接种计划对年轻女性性行为的影响，我们了解多少？HPV 疫苗接种并未与年轻女性的性行为风险增加相关。然而，目前的研究存在一些重要的局限性，未来的研究应侧重于包括疫苗接种前基线测量、可能的混杂因素调整以及临床指标和行为结果测量的纵向设计。
