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加权毒性评分的优缺点。

Advantages and Adversities of the Weighted Toxicity Score.

机构信息

Department of Oncology, Karmanos Cancer Institute/Wayne State University, Detroit, Michigan.

出版信息

Clin Cancer Res. 2018 Oct 15;24(20):4918-4920. doi: 10.1158/1078-0432.CCR-18-1562. Epub 2018 Jul 12.

DOI:10.1158/1078-0432.CCR-18-1562
PMID:30002079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6191346/
Abstract

It is imperative to develop a comprehensive toxicity score that will capture, convey, and compare adverse events of agents that are therapeutic options for the same disease state. The weighted toxicity score tool is a valuable aid in the shared decision-making process of therapeutic choice between patients and providers. .

摘要

开发一种全面的毒性评分系统至关重要，该系统能够捕捉、传递和比较针对同一疾病状态的治疗选择药物的不良事件。加权毒性评分工具是患者和提供者在治疗选择的共同决策过程中的有价值的辅助工具。

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本文引用的文献

1
A Method to Summarize Toxicity in Cancer Randomized Clinical Trials.一种总结癌症随机临床试验中毒性的方法。
Clin Cancer Res. 2018 Oct 15;24(20):4968-4975. doi: 10.1158/1078-0432.CCR-17-3314. Epub 2018 May 8.
2
Evolving Treatment Paradigm in Metastatic Renal Cell Carcinoma.转移性肾细胞癌不断演变的治疗模式
Am Soc Clin Oncol Educ Book. 2017;37:319-329. doi: 10.1200/EDBK_174469.
3
The Imperative for a New Approach to Toxicity Analysis in Oncology Clinical Trials.肿瘤临床试验中进行毒性分析的新方法势在必行。
J Natl Cancer Inst. 2015 Aug 1;107(10). doi: 10.1093/jnci/djv216. Print 2015 Oct.
4
Patient-reported outcomes and the evolution of adverse event reporting in oncology.患者报告的结局与肿瘤学中不良事件报告的演变
J Clin Oncol. 2007 Nov 10;25(32):5121-7. doi: 10.1200/JCO.2007.12.4784.
5
Assessing the reliability of two toxicity scales: implications for interpreting toxicity data.评估两种毒性量表的可靠性：对毒性数据解读的启示
J Natl Cancer Inst. 1993 Jul 21;85(14):1138-48. doi: 10.1093/jnci/85.14.1138.