Shams Vahdati Samad, Ala Alireza, Mousavi Aghdas Seyed Ali, Adib Ali, Mirza-Aghazadeh-Attari Mohammad, Aliar Fatemeh
Department of Emergency, Emergency Medicine Research Team, Tabriz University of Medical Sciences, Iran.
Department of Emergency Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Eurasian J Med. 2018 Jun;50(2):86-90. doi: 10.5152/eurasianjmed.2018.17322. Epub 2018 Jun 1.
Stroke is a common heterogeneous disease classified into two subtypes: ischemic and hemorrhagic. Many risk factors have been associated with stroke, and the most well-known is hypertension. Although the relation between stroke and these risk factors has been emphasized before, there is inconclusive evidence about the relation between the different risk factors and the subtypes of stroke. The present study aims to fill this gap.
In the present retrospective, cross-sectional study, 827 patients with diagnosed stroke were included. Demographic data and the acquired risk factors were determined using pre-designed questionnaires. Statistical analysis was conducted using chi-square test, Student t-test, and Pearson correlation coefficient.
Among the included 827 patients, 432 (52.2%) were men and 395 (47.8%) were women. The mean±standard deviation of age was 68.41±12.46 y in men and 67.89±11.85 y in women, respectively, and the difference was not significant. Of all the patients, 672 had ischemic strokes and 155 had hemorrhagic strokes. The most common risk factor in the patients was hypertension with a prevalence of 66.7%. Of all the risk factors, only hypertension, atrial fibrillation (AF), age, and a positive family history were significantly related to a subtype of stroke.
Knowing that the prevalence of hypertension, AF, age, and positive family history are significantly different between the two subtypes, the patients having these risk factors can be entered into more specified public health measures, which puts more emphasis on the subtype that they are more prone to.
中风是一种常见的异质性疾病,分为缺血性和出血性两种亚型。许多风险因素与中风有关,其中最广为人知的是高血压。尽管之前已经强调了中风与这些风险因素之间的关系,但关于不同风险因素与中风亚型之间的关系,证据并不确凿。本研究旨在填补这一空白。
在本回顾性横断面研究中,纳入了827例已确诊中风的患者。使用预先设计的问卷确定人口统计学数据和获得的风险因素。采用卡方检验、学生t检验和皮尔逊相关系数进行统计分析。
在所纳入的827例患者中,男性432例(52.2%),女性395例(47.8%)。男性年龄的均值±标准差为68.41±12.46岁,女性为67.89±11.85岁,差异无统计学意义。所有患者中,672例为缺血性中风,155例为出血性中风。患者中最常见的风险因素是高血压,患病率为66.7%。在所有风险因素中,只有高血压、心房颤动(AF)、年龄和家族史阳性与中风亚型显著相关。
鉴于高血压、AF、年龄和家族史阳性在两种亚型之间的患病率存在显著差异,对于有这些风险因素的患者,可以采取更具体的公共卫生措施,更侧重于他们更易患的亚型。