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一名患有糖尿病肾病且疑似播散性肺结核的54岁男性:罕见诊断中的临床病理相关性

A 54-year-old male with diabetic nephropathy and suspected disseminated tuberculosis: Clinicopathologic correlation in a rare diagnosis.

作者信息

Misra Pratibha, Jassar Aneeta, Ghosh Arijit Kumar

机构信息

Department of Pathology, Military Hospital, Jalandhar, Punjab, India.

Department of Medicine, Military Hospital, Jalandhar, Punjab, India.

出版信息

Indian J Pathol Microbiol. 2018 Jul-Sep;61(3):383-388. doi: 10.4103/IJPM.IJPM_728_17.

DOI:10.4103/IJPM.IJPM_728_17
PMID:30004060
Abstract

Tuberculosis (TB) and Non-Hodgkins lymphoma (NHL) share similar clinical and radiological features, which make diagnosis a challenge. It is often difficult to rule out a diagnosis of extrapulmonary and/or disseminated TB because of its paucibacillary nature and difficulty in accessing the involved organs. In countries with high prevalence of TB like ours, empirical antitubercular treatment (ATT) is started, and the patient is followed up closely for response. We present a rare case of a 54-year old diabetic male who was suspected to be a case of disseminated TB but had a rapid downhill course despite ATT. A postmortem revealed features of a rare, aggressive T-cell NHL masquerading as disseminated TB.

摘要

结核病(TB)和非霍奇金淋巴瘤(NHL)具有相似的临床和影像学特征,这使得诊断成为一项挑战。由于肺外和/或播散性结核病的菌量少且难以对受累器官进行取材,往往难以排除该诊断。在像我们国家这样结核病高流行的国家,会开始经验性抗结核治疗(ATT),并对患者进行密切随访以观察反应。我们报告一例罕见病例,一名54岁的糖尿病男性,怀疑为播散性结核病,但尽管接受了ATT,病情仍迅速恶化。尸检显示为罕见的侵袭性T细胞NHL,伪装成播散性结核病。

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