Masamatti Smita S, Vijaya C, Narasimha Aparna
Department of Pathology, Sapthagiri Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, India.
Indian J Pathol Microbiol. 2018 Jul-Sep;61(3):428-430. doi: 10.4103/IJPM.IJPM_101_17.
Chondroid syringoma (CS) also known as mixed tumor of the skin, is a rare benign adnexal tumor accounting for < 0.098%. Epithelial cells arranged in cords and tubules set in myxoid or chondroid stroma. Differentiation such as osteoid, sebaceous or mature adipocytes can be seen rarely. Hyaline cell rich is a rare variant of CS composed of cells with eosinophilic hyaline cytoplasm and plasmacytoid features. CS can have benign, atypical and malignant variants. The term atypical mixed tumor is recommended for those tumors which have histological features of malignancy such as infiltrative margin, satellite tumor nodules and tumor necrosis but without proven metastasis. Very few case reports of hyaline cellrich benign CS have been reported in the past, but to the best of our knowledge, possibly it is the first case of atypical hyaline cellrich CS of the little finger in a 65 year-old female showing divergent differentiation.
软骨样汗腺腺瘤（CS）也称为皮肤混合瘤，是一种罕见的良性附属器肿瘤，占比小于0.098%。上皮细胞排列成条索状和小管状，位于黏液样或软骨样基质中。罕见可见类骨质、皮脂腺或成熟脂肪细胞等分化。富含透明细胞是CS的一种罕见变体，由具有嗜酸性透明细胞质和浆细胞样特征的细胞组成。CS可分为良性、非典型性和恶性变体。对于那些具有浸润性边缘、卫星瘤结节和肿瘤坏死等恶性组织学特征但未证实有转移的肿瘤，建议使用非典型混合瘤这一术语。过去很少有关于富含透明细胞的良性CS的病例报告，但据我们所知，这可能是首例65岁女性小指非典型富含透明细胞CS且表现出不同分化的病例。
