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年轻女性的转移性子宫苗勒管腺肉瘤:诊断难题。

Metastasizing uterine mullerian adenosarcoma in a young female: Diagnostic enigma.

作者信息

Patnayak Rashmi, Rukmangadha Nandyala, Architha Pabbu, Reddy Gajjala Sivanath, Lakshmi Amarchala Yadagiri, Kannan Thiruvengadaswamy, Jena Amitabh

机构信息

Department of Pathology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

Department of Surgical Oncology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

出版信息

Indian J Pathol Microbiol. 2018 Jul-Sep;61(3):440-442. doi: 10.4103/IJPM.IJPM_1_18.

Abstract

Uterine adenosarcomas are uncommon tumors. It is a biphasic tumor with both epithelial and mesenchymal component. The epithelial component is benign in nature, and the mesenchymal component is malignant. Metastasis is rare in adenosarcoma. We report a case of adenosarcoma with lymph nodal metastasis. A 20-year-old female presented with history of per vaginal bleeding for 1 month. Per vaginal examination revealed a fungating mass protruding through the cervical os. Ultrasonography and magnetic resonance imaging showed a large intrauterine mass. Biopsy of the mass done at an outside hospital was reported as rhabdomyosarcoma. Hence, she was given one cycle of neoadjuvant chemotherapy. Following this, she had profuse bleeding. Emergency hysterectomy with pelvic lymph nodal dissection was performed. The final histopathology was reported as adenosarcoma. One pelvic lymph node showed metastatic deposit of rhabdomyosarcomatous element. In young females presenting with polypoidal mass, uterine adenosarcoma can be considered in the differential diagnosis.

摘要

子宫腺肉瘤是罕见肿瘤。它是一种具有上皮和间质成分的双相肿瘤。上皮成分本质上是良性的,间质成分是恶性的。腺肉瘤转移罕见。我们报告一例伴有淋巴结转移的腺肉瘤病例。一名20岁女性,有1个月的经阴道出血史。经阴道检查发现一个蕈状肿物从宫颈口突出。超声检查和磁共振成像显示子宫内有一个大肿物。在外院对该肿物进行活检,报告为横纹肌肉瘤。因此,她接受了一个周期的新辅助化疗。此后,她出现大量出血。遂行急诊子宫切除术及盆腔淋巴结清扫术。最终组织病理学报告为腺肉瘤。一个盆腔淋巴结显示有横纹肌肉瘤成分的转移灶。对于出现息肉样肿物的年轻女性,鉴别诊断时可考虑子宫腺肉瘤。

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