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一项多中心横断面研究,调查南非西开普省择期手术患者中高血压疾病的患病率。

A multicentre, cross-sectional study investigating the prevalence of hypertensive disease in patients presenting for elective surgery in the Western Cape Province, South Africa.

作者信息

Van der Spuy K, Crowther M, Nejthardt M, Roodt F, Davids J, Roos J, Cloete E, Pretorius T, Davies G, Van der Walt J, Van der Westhuizen C, Flint M, Swanevelder J, Biccard B

机构信息

Department of Anaesthesia and Perioperative Medicine, Groote Schuur Hospital and Faculty of Health Sciences, University of Cape Town, South Africa.

出版信息

S Afr Med J. 2018 Jun 26;108(7):590-595. doi: 10.7196/SAMJ.2018.v108i7.13022.

Abstract

BACKGROUND

Hypertension is common, affecting over one billion people worldwide. In sub-Saharan Africa, hypertensive disease not only affects the older population but is becoming increasingly prevalent in younger individuals. In South Africa (SA), >30% of the adult population has hypertension, making it the single most common cardiovascular risk factor and the predominant contributor to cardiovascular disease and mortality. Elevated blood pressure is the most common perioperative comorbidity encountered in non-cardiac surgical patients, with an overall prevalence of 20 - 25%, and it remains poorly controlled in low- and middle-income countries. Hypertension in the perioperative setting may adversely affect patient outcome. It therefore not only flags possible perioperative challenges to anaesthesiologists, but also identifies patients at risk of long-term morbidity and mortality.

OBJECTIVES

To determine the prevalence and severity of hypertension in elective adult surgical patients in the Western Cape Province, SA.

RESULTS

The study population included all elective surgical patients from seven hospitals in the Western Cape during a 1-week period. Hypertension, defined as having had a previous diagnosis of hypertension or meeting the blood pressure criteria of >140/90 mmHg, was identified in 51.8% of patients during preoperative assessment. Significantly, newly diagnosed hypertension was present in 9.9% of all patients presenting for elective surgery. Although 98.1% of the known hypertensive patients were on antihypertensive therapy, 36.9% were inadequately controlled. There are numerous reasons for this, but notably 32.1% of patients admitted to forgetting to take their medication, making patient factors the most common reason for treatment non-compliance.

CONCLUSIONS

The perioperative period may be an important opportunity to identify undiagnosed hypertensive patients. The perioperative encounter may have a significant public health implication in facilitating appropriate referral and treatment of patients with hypertension to decrease long-term cardiovascular complications in SA.

摘要

背景

高血压很常见,全球有超过10亿人受其影响。在撒哈拉以南非洲,高血压疾病不仅影响老年人群,在年轻人中也越来越普遍。在南非,超过30%的成年人口患有高血压,这使其成为最常见的单一心血管危险因素,也是心血管疾病和死亡率的主要促成因素。血压升高是非心脏手术患者围手术期最常见的合并症,总体患病率为20% - 25%,在低收入和中等收入国家,血压控制情况仍然很差。围手术期的高血压可能会对患者的预后产生不利影响。因此,它不仅向麻醉医生提示了可能的围手术期挑战,还能识别出有长期发病和死亡风险的患者。

目的

确定南非西开普省择期成年手术患者中高血压的患病率和严重程度。

结果

研究人群包括西开普省七家医院在1周内的所有择期手术患者。在术前评估中,51.8%的患者被确定患有高血压,定义为既往有高血压诊断或血压标准满足>140/90 mmHg。值得注意的是,所有择期手术患者中有9.9%为新诊断的高血压。尽管98.1%的已知高血压患者正在接受抗高血压治疗,但36.9%的患者血压控制不佳。原因有很多,但值得注意的是,32.1%的患者承认忘记服药,这使得患者因素成为治疗不依从的最常见原因。

结论

围手术期可能是识别未诊断高血压患者的重要时机。围手术期接触对于促进高血压患者的适当转诊和治疗,以减少南非的长期心血管并发症可能具有重大的公共卫生意义。

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