横断面研究比较原发性乙肝免疫后肯尼亚感染和未感染 HIV 的儿童的乙肝免疫。
A Cross-sectional Study to Compare Hepatitis B Immunity in HIV-infected and HIV-uninfected Kenyan Children After Primary Hepatitis B Immunization.
机构信息
From the Gertrude's Children's Hospital, Nairobi, Kenya.
LVCT Health, Nairobi, Kenya.
出版信息
Pediatr Infect Dis J. 2018 Aug;37(8):e214-e215. doi: 10.1097/INF.0000000000001902.
PMID:30004392
Abstract
To evaluate protective antibody levels against hepatitis B surface antigen in HIV-infected and HIV-uninfected Kenyan children, this study enrolled 531 children. In the HIV-infected group, only 18.3% had protective hepatitis B surface antigen compared with 74.4% in the HIV-uninfected group (P < 0.0001). Perhaps HIV-infected children should be immunized differently.
摘要
为了评估肯尼亚感染和未感染 HIV 的儿童体内针对乙型肝炎表面抗原的保护性抗体水平，本研究纳入了 531 名儿童。在感染 HIV 的儿童组中，仅有 18.3%的儿童具有保护性乙型肝炎表面抗原，而在未感染 HIV 的儿童组中，这一比例为 74.4%（P<0.0001）。也许 HIV 感染儿童应该接受不同的免疫接种。
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