Blons Charlie, Mallet-Ladeira Sonia, Amgoune Abderrahmane, Bourissou Didier
CNRS/Université Paul Sabatier, Laboratoire Hétérochimie Fondamentale et Appliquée (LHFA, UMR 5069), 118 Route de Narbonne, 31062, Toulouse Cedex 09, France.
Institut de Chimie de Toulouse (FR 2599), 118 Route de Narbonne, 31062, Toulouse Cedex 09, France.
Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11732-11736. doi: 10.1002/anie.201807106. Epub 2018 Aug 1.
The first catalytic application of well-defined (P,C) cyclometalated gold(III) complexes is reported. The bench-stable bis(trifluoroacetyl) complexes 2 a,b perform very well in the intermolecular hydroarylation of alkynes. The reaction is broad in scope, it proceeds within few hours at 25 °C at catalytic loadings of 0.1-5 mol %. The electron-rich arene adds across the C≡C bond with complete regio- and stereo-selectivity. The significance of well-defined gold(III) complexes and ligand design are highlighted in a powerful but challenging catalytic transformation.
报道了结构明确的（磷，碳）环金属化金（III）配合物的首次催化应用。稳定性良好的双（三氟乙酰基）配合物2 a,b在炔烃的分子间氢芳基化反应中表现出色。该反应适用范围广，在25 °C下，催化负载量为0.1 - 5 mol %时，反应在数小时内即可完成。富电子芳烃以完全的区域和立体选择性加成到C≡C键上。在一个强大但具有挑战性的催化转化中，突出了结构明确的金（III）配合物和配体设计的重要性。
