Sanoja Ivanna A, Toth Kenneth S
From the Department of Anesthesiology and Pain Management, John H. Stroger Jr. Hospital of Cook County, Chicago Illinois.
A A Pract. 2019 Jan 1;12(1):22-24. doi: 10.1213/XAA.0000000000000834.
We report the case of a 60-year-old man who underwent open radical prostatectomy for prostate adenocarcinoma. He had no known cardiac disease or symptoms other than controlled hypertension and remote history of cocaine use. The patient was given sugammadex for reversal of neuromuscular blockade and, within 1 minute, developed severe, drug-resistant bradycardia followed by pulseless electrical activity arrest. Advanced cardiac life support was initiated and continued for 15 minutes before the return of spontaneous circulation. Subsequent cardiac workup showed no abnormalities. We believe the cause of arrest was sugammadex, considering the time of administration, the absence of cardiac disease, and stable operative course.
我们报告了一例60岁男性患者，其因前列腺腺癌接受了开放性根治性前列腺切除术。除了得到控制的高血压和既往可卡因使用史外，他没有已知的心脏疾病或症状。该患者接受了舒更葡糖用于逆转神经肌肉阻滞，在1分钟内，出现了严重的、耐药性心动过缓，随后是无脉电活动心脏骤停。启动了高级心脏生命支持并持续了15分钟，之后恢复了自主循环。随后的心脏检查未发现异常。考虑到给药时间、无心脏疾病以及手术过程平稳，我们认为心脏骤停的原因是舒更葡糖。
