Lorenc Z Paul, Goldberg David, Nestor Mark
J Drugs Dermatol. 2018 Jul 1;17(7):786-793.
Absorbable suspension sutures for tissue repositioning represent a minimally invasive approach to facial rejuvenation. With 2015 FDA 510(k) approval of Silhouette InstaLift™ (Sinclair Pharma, Irvine, CA), a completely absorbable device comprised of 82% PLLA/18% PLGA sutures and bi-directional cones, came the challenge of developing optimal technique for achieving effective, precise, and durable tissue repositioning. Here, the authors discuss the importance of straight-line vector planning (SLVP) and positioning of the suture perpendicular to the plane to be elevated in obtaining optimal results for tissue repositioning. Both the scientific underpinnings of SLVP are presented, along with detailed discussion of technique for suture placement in the mid-face, jawline/jowls, and neck.
The authors are some of the earliest adopters of absorbable suspension sutures in the United States and have both used InstaLift™ sutures for tissue repositioning and facial recontouring in treatment of more than 500 patients and developed the principles of SLVP as a method to ensure optimal outcomes.
Patient case studies illustrating the importance of SLVP are presented. In over 500 patients treated within the authors' practices since InstaLift approval there have been no serious adverse events and noticeable bruising has occurred in less than 5% of patients. Results of repositioning and recontouring are evident for up to 24 months.
Absorbable suspension sutures are a highly adaptable, non-invasive device for lifting and repositioning of descended facial tissue. Outcomes are dependent upon proper technique, including SLVP. J Drugs Dermatol. 2018;17(7):786-793.
用于组织复位的可吸收悬吊缝线是一种微创面部年轻化方法。随着2015年美国食品药品监督管理局（FDA）对Silhouette InstaLift™（辛克莱制药公司，加利福尼亚州欧文市）的510(k)批准，该完全可吸收装置由82%聚左旋乳酸（PLLA）/18%聚乳酸-羟基乙酸共聚物（PLGA）缝线和双向锥体组成，出现了开发实现有效、精确和持久组织复位的最佳技术的挑战。在此，作者讨论了直线矢量规划（SLVP）以及将缝线垂直于待提升平面放置在获得组织复位最佳效果中的重要性。介绍了SLVP的科学依据，并详细讨论了中面部、下颌缘/下颌赘肉和颈部缝线放置技术。
作者是美国最早采用可吸收悬吊缝线的一批人，既使用InstaLift™缝线进行组织复位和面部重塑，治疗了500多名患者，还制定了SLVP原则作为确保最佳效果的方法。
展示了说明SLVP重要性的患者案例研究。自InstaLift获批以来，在作者的实践中治疗的500多名患者中，没有发生严重不良事件，不到5%的患者出现明显瘀伤。复位和重塑效果可持续长达24个月。
可吸收悬吊缝线是一种用于提升和复位下垂面部组织的高度适应性强、非侵入性的装置。结果取决于正确的技术，包括SLVP。《药物皮肤病学杂志》。2018；17(7)：786 - 793。
