Department of Epilepsy, Movement Disorders and Physiology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan; Department of Medical Science Technology, School of Health Science at Fukuoka, International University of Health and Welfare, 137-1 Enokizu, Okawa, Fukuoka 831-8501, Japan.
Department of Epilepsy, Movement Disorders and Physiology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Clin Neurophysiol. 2018 Sep;129(9):1884-1890. doi: 10.1016/j.clinph.2018.05.015. Epub 2018 Jun 15.
Neuro-feedback (NFB) training by the self-regulation of slow potentials (SPs) <0.5 Hz recorded from the vertex scalp has been applied for seizure suppression in patients with epilepsy. However, SP is highly susceptible to artifact contamination, such as the galvanic skin response (GSR). This study aimed to evaluate the correlation between SPs recorded from the scalp and intracranial electroencephalography (EEG) by event-related coherence analysis.
The scalp and subdural SPs were simultaneously recorded during NFB training by the DC-EEG machine while undergoing invasive recordings before epilepsy surgery in 10 patients with refractory partial epilepsy. The SPs at the vertex electrode were used as a reference for coherence analysis.
The coherence of SPs negatively correlated with the distance between the subdural and scalp electrodes. A significant negative correlation was noted between the linear subdural-scalp electrode distance and the coherence value (r = - 0.916, p < 0.001).
Scalp-recorded SPs from the vertex area primarily reflect the cortical activity of high lateral convexity.
Our results strongly suggest that SPs in NFB recorded from the vertex scalp electrode is derived from the cortices of high lateral convexity but not from the artifacts, such as GSR.
通过自我调节从顶点头皮记录的慢电位（SP）<0.5 Hz 进行神经反馈（NFB）训练，已应用于癫痫患者的癫痫发作抑制。然而，SP 非常容易受到伪影污染，如皮肤电反应（GSR）。本研究旨在通过事件相关相干分析评估头皮和颅内脑电图（EEG）记录的 SP 之间的相关性。
在 10 例难治性部分性癫痫患者接受癫痫手术前的侵入性记录期间，使用 DC-EEG 机器同时记录 NFB 训练期间的头皮和硬膜下 SP。将顶点电极上的 SP 用作相干分析的参考。
SP 的相干性与硬膜下和头皮电极之间的距离呈负相关。线性硬膜下-头皮电极距离与相干值之间存在显著负相关（r= -0.916，p<0.001）。
从顶点区域记录的头皮 SP 主要反映了高外侧凸面的皮质活动。
我们的结果强烈表明，从顶点头皮电极记录的 NFB 中的 SP 源自高外侧凸面的皮质，而不是来自 GSR 等伪影。
