Pathology Unit, Department of Pathology and Diagnostic, University and Hospital Trust of Verona, Verona, Italy.
Pathology Unit, Department of Pathology and Diagnostic, University and Hospital Trust of Verona, Verona, Italy.
Cardiovasc Pathol. 2018 Sep-Oct;36:25-29. doi: 10.1016/j.carpath.2018.06.001. Epub 2018 Jun 10.
Mesothelial/monocytic incidental cardiac excrescence (MICE) is a benign lesion composed of histiocytes and mesothelial cells, usually found during cardiac surgery. To date, no more than 50 cases are reported in literature, and pathogenesis is still unclear even if different theories have been proposed. Here we report a case of MICE encountered during aortic valve replacement with typical histological features and extensive immunohistochemical investigation. To date, little information is available about the pathogenesis of MICE. We review the current literature focusing on the role of adhesion molecules such as CD31.
间皮/单核细胞偶然性心脏赘生物（MICE）是一种良性病变，由组织细胞和间皮细胞组成，通常在心脏手术中发现。迄今为止，文献中报道的病例不超过 50 例，尽管提出了不同的理论，但发病机制仍不清楚。在此，我们报告一例在主动脉瓣置换术中遇到的 MICE 病例，具有典型的组织学特征和广泛的免疫组织化学研究。迄今为止，关于 MICE 的发病机制的信息很少。我们回顾了目前的文献，重点关注粘附分子如 CD31 的作用。
