Dawoud Sara, Solomon Rachele J, Eyerly-Webb Stephanie A, Abrahams Neil A, Pedraza Fernando, Arenas Juan D, Hranjec Tjasa
Medical Student in the College of Osteopathic Medicine at Nova Southeastern University in Fort Lauderdale, FL.
Research Coordinator in the Office of Human Research at Memorial Regional Hospital in Hollywood, FL.
Perm J. 2018;22:17-150. doi: 10.7812/TPP/17-150.
Xanthogranulomatous inflammation, characterized by destruction and replacement of tissues with chronic inflammatory cells, including foamy histiocytes and hemosiderin-laden macrophages, is uncommon. In patients with xanthogranulomatous pyelonephritis, inflammation may extend from the kidney to the overlying duodenum, creating a pyeloduodenal fistula that further complicates medical and surgical management. We present two cases with recurrent kidney infections who each ultimately received a nephrectomy and repair of their duodenal fistula.
黄色肉芽肿性炎症以组织被慢性炎症细胞破坏和取代为特征,这些慢性炎症细胞包括泡沫状组织细胞和含铁血黄素巨噬细胞,较为罕见。在黄色肉芽肿性肾盂肾炎患者中,炎症可能从肾脏蔓延至上方的十二指肠,形成肾盂十二指肠瘘,这进一步使药物和手术治疗变得复杂。我们报告两例复发性肾脏感染患者,他们最终均接受了肾切除术及十二指肠瘘修补术。