Department of General Surgery, UT Health San Antonio, 7703 Floyd Curl Drive, Mail Code 7737, San Antonio, TX 78229, USA.
Department of Surgery, University at Buffalo, 100 High Street, C317, Buffalo, NY 14203, USA.
Surg Clin North Am. 2018 Aug;98(4):869-876. doi: 10.1016/j.suc.2018.03.013. Epub 2018 May 21.
Sarcoma of the breast is extremely rare and differs from epithelial breast carcinomas in staging and treatment. Diagnostic workup includes breast imaging and core biopsy as in breast epithelial carcinoma. Surgical management is often wide local excision in the form of breast conservation if possible for primary breast sarcoma or total mastectomy. Radiation-associated breast angiosarcomas often require total mastectomy with radical excision of skin. Breast sarcomas have a hematogenous spread so lymph node evaluation is not a part of treatment or staging. Local recurrence rates are high; prognosis remains poor despite on-going advances in the treatment of epithelial breast carcinoma.
乳房肉瘤极为罕见,在分期和治疗方面有别于乳腺上皮癌。诊断工作包括乳腺成像和核心活检,与乳腺上皮癌相同。如果可能,原发性乳腺肉瘤的外科治疗通常是广泛局部切除(保乳)或全乳切除术。与放射相关的乳腺血管肉瘤常需要全乳切除术和皮肤根治性切除。乳腺肉瘤有血行播散,因此淋巴结评估不是治疗或分期的一部分。局部复发率高;尽管上皮性乳腺癌的治疗不断取得进展,但预后仍然较差。