Department of Circulatory Emergency and Resuscitation Science, Kanazawa University Graduate School of Medicine, Japan.
Emergency Medical Centre, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Resuscitation. 2018 Sep;130:92-98. doi: 10.1016/j.resuscitation.2018.07.011. Epub 2018 Jul 10.
Japanese emergency medical services (EMS) personnel providing advance life support confirm the absence of a carotid pulse before initiating chest compressions (CCs) in adult out-of-hospital cardiac arrest (OHCA). This study aims to investigate the efficacy of a new protocol facilitating early CCs before definitive cardiac arrest in enhancing the outcomes of OHCA.
The 2011 new protocol facilitated EMS to initiate CCs when the carotid pulse was weak and/or <50/min in comatose adult patients with respiratory arrest (apnoea or agonal breathing) and loss of the radial pulse. During 2008-2015, we compared the neurologically favourable 1-year survival rate of EMS-witnessed OHCA and EMS-confirmed out-of-hospital respiratory arrest (OHRA) in adults before (N = 257 and 34, respectively) and after (N = 255 and 54, respectively) the implementation of the new protocol.
After the new protocol, EMS initiated CCs >1.5 min before definitive cardiac arrest in 31% (80/255) and 33% (18/54) of EMS-witnessed OHCA and EMS-confirmed OHRA, respectively. While the new protocol was not significantly associated with survival of EMS-confirmed OHRA, it was significantly associated with survival of EMS-witnessed OHCA: 9.0% and 14.9%, before and after, P by univariate analysis <0.03; adjusted OR (95% CI) by multivariable logistic regression analysis, 2.01 (1.04-3.90). Neither early start of CCs nor the new protocol was associated with the progression to cardiac arrest in 212 cases with impending cardiac arrest.
A new EMS protocol facilitating early CCs before definitive cardiac arrest was associated with higher survival of EMS-witnessed OHCA.
日本的急救医疗服务(EMS)人员在对院外心脏骤停(OHCA)成人进行胸外按压(CCs)前,会先确认颈动脉搏动是否消失。本研究旨在探讨一项新的方案,即在明确心脏骤停前促进早期 CCs,是否能提高 OHCA 的预后。
2011 年新方案规定,当 EMS 人员在昏迷、有呼吸停止(无呼吸或濒死样呼吸)和桡动脉搏动消失的成年患者中发现颈动脉搏动微弱或<50 次/分时,即可启动 CCs。在 2008-2015 年期间,我们比较了新方案实施前后(分别为 N=257 和 34 例)EMS 目击 OHCA 和 EMS 确认的院外呼吸停止(OHRA)成年患者中神经功能良好的 1 年生存率。
新方案实施后,31%(80/255)和 33%(18/54)的 EMS 目击 OHCA 和 EMS 确认 OHRA 患者在明确心脏骤停前超过 1.5 分钟开始 CCs。虽然新方案与 EMS 确认的 OHRA 存活率无显著相关性,但与 EMS 目击 OHCA 存活率显著相关:未经单因素分析 P<0.03,分别为 9.0%和 14.9%;经多变量逻辑回归分析调整后 OR(95%CI)为 2.01(1.04-3.90)。在 212 例即将发生心脏骤停的患者中,早期开始 CCs 或新方案均与进展为心脏骤停无关。
促进明确心脏骤停前早期 CCs 的新 EMS 方案与 EMS 目击 OHCA 的生存率提高有关。