Rea Corinna J, Tran Katherine D, Jorina Maria, Wenren Larissa M, Hawryluk Elena B, Toomey Sara L
1 Boston Children's Hospital, Boston, MA, USA.
2 Harvard Medical School, Boston, MA, USA.
Clin Pediatr (Phila). 2018 Nov;57(13):1506-1514. doi: 10.1177/0009922818787295. Epub 2018 Jul 16.
We investigated factors associated with quality of life (QOL) in children with eczema. We conducted a cross-sectional analysis of survey data from 224 parents of children with eczema attending a large, hospital-based pediatric clinic. Parents completed a validated eczema severity scale (Patient-Oriented Eczema Measure), a QOL scale (Infants' Dermatitis QOL Index or Children's Dermatology Life Quality Index), and a knowledge and understanding questionnaire. In adjusted multivariate analyses, worse eczema severity was associated with worse overall QOL (β = 0.5; 95% confidence interval [CI] = [0.5, 0.6]), while a higher knowledge score was associated with better QOL (β = -3.4; 95% CI = [-6.6, -0.2]). Similarly, even after adjustment for eczema severity, greater understanding of a child's individual treatment plan was associated with better QOL (β = -0.7; 95% CI = [-1.4, -0.08]), while increased frequency of worrying about a child's eczema was associated with worse QOL (β = 0.7; 95% CI = [0.03, 1.1]). These results suggest primary care providers may be able to influence QOL through optimal eczema management and family education.
我们调查了与湿疹患儿生活质量（QOL）相关的因素。我们对来自一家大型医院儿科诊所的224名湿疹患儿家长的调查数据进行了横断面分析。家长们完成了一份经过验证的湿疹严重程度量表（患者导向性湿疹测量量表）、一份生活质量量表（婴儿皮炎生活质量指数或儿童皮肤病生活质量指数）以及一份知识与理解问卷。在调整后的多变量分析中，更严重的湿疹与更差的总体生活质量相关（β = 0.5；95%置信区间[CI] = [0.5, 0.6]），而更高的知识得分与更好的生活质量相关（β = -3.4；95% CI = [-6.6, -0.2]）。同样，即使在调整了湿疹严重程度之后，对孩子个体治疗方案的更多理解与更好的生活质量相关（β = -0.7；95% CI = [-1.4, -0.08]），而对孩子湿疹担忧频率的增加与更差的生活质量相关（β = 0.7；95% CI = [0.03, 1.1]）。这些结果表明，初级保健提供者或许能够通过优化湿疹管理和家庭教育来影响生活质量。
