Universidad de Oviedo.
Psicothema. 2018 Aug;30(3):316-321. doi: 10.7334/psicothema2017.401.
Over the last decade there has been growing evidence that neuropsychological deficits, principally in the executive functions, may be involved in the pathogenesis of Chiari Type I disease. The aim of this study is to compare changes in cognitive function in patients with Chiari Type I and healthy subjects.
The neuropsychological profile of these patients was compared with healthy controls. Three neuropsychological tests were administered to both Chiari Type I patients and healthy controls to assess the frontal executive functions of vigilance or selective attention, mental flexibility, planning and concept formation.
The results suggest that Chiari Type I patients are affected in the processes of inhibition and self-control as well as in attention capacity and maintaining a course of thought and action.
These results provide evidence of possible deficits or anomalies in the cognitive executive functions of patients with Chiari Type I.
在过去的十年中，越来越多的证据表明神经心理学缺陷，主要是在执行功能方面，可能与 Chiari Ⅰ型疾病的发病机制有关。本研究的目的是比较 Chiari Ⅰ型患者和健康受试者认知功能的变化。
将这些患者的神经心理学特征与健康对照组进行比较。对 Chiari Ⅰ型患者和健康对照组进行了三项神经心理学测试，以评估警觉或选择性注意、心理灵活性、计划和概念形成的额叶执行功能。
结果表明，Chiari Ⅰ型患者在抑制和自我控制过程中，以及在注意力容量和维持思维和行动过程中都受到影响。
这些结果提供了 Chiari Ⅰ型患者认知执行功能可能存在缺陷或异常的证据。
