壳聚糖/聚乙烯醇薄膜的制备及其对铜绿假单胞菌 PAO1 生物膜形成的抑制作用。
Preparation of chitosan/poly vinyl alcohol films and their inhibition of biofilm formation against Pseudomonas aeruginosa PAO1.
机构信息
College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, PR China.
Jiangsu Key Laboratory of Regional Resource Exploitation and Medicinal Research, Huaiyin Institute of Technology, Huaian 223003, PR China.
出版信息
Int J Biol Macromol. 2018 Oct 15;118(Pt B):2131-2137. doi: 10.1016/j.ijbiomac.2018.07.061. Epub 2018 Jul 19.
Poly (vinyl alcohol) (PVA) and chitosan (CH)-based blend films were prepared via a simple mixing and casting method. The films were characterized by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and ultraviolet-visible spectroscopy (UV-vis). Mechanical properties, thermogravimetric (TG), derivative thermogravimetric (DTG), and the inhibition of biofilm formation against Pseudomonas aeruginosa PAO1 (P. aeruginosa PAO1) of CH/PVA films were investigated. The results indicated that CH and PVA in the blend films interacted by physical crosslinks consisting of intermolecular hydrogen bonds and intermolecular hydrogen bonds with compatibility, and were more thermally-stable than that of PVA. CH addition decreased the tensile strength and the light transmittance. CH60:PVA40 film showed notable activity against adhesion and inhibited biofilm formation of P. aeruginosa PAO1, indicating that CH60:PVA40 film could be applied as an antimicrobial and biofilm inhibiting food packaging material.
聚乙烯醇（PVA）和壳聚糖（CH）基共混膜通过简单的混合和浇铸法制备。通过傅里叶变换红外光谱（FT-IR）、扫描电子显微镜（SEM）和紫外可见光谱（UV-vis）对薄膜进行了表征。研究了壳聚糖/聚乙烯醇薄膜的力学性能、热重（TG）、导数热重（DTG）和对铜绿假单胞菌 PAO1（P. aeruginosa PAO1）生物膜形成的抑制作用。结果表明，共混膜中的 CH 和 PVA 之间通过包含分子间氢键和分子间氢键的物理交联相互作用，具有相容性，且热稳定性优于 PVA。CH 的加入降低了拉伸强度和透光率。CH60：PVA40 薄膜对黏附具有显著的活性，并抑制铜绿假单胞菌 PAO1 的生物膜形成，表明 CH60：PVA40 薄膜可用作抗菌和抑制生物膜的食品包装材料。
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