Reiser S, Hallfrisch J, Fields M, Powell A, Mertz W, Prather E S, Canary J J
Am J Clin Nutr. 1986 Jan;43(1):151-9. doi: 10.1093/ajcn/43.1.151.
Ten men and nine women were studied to determine whether replacement of utilizable complex carbohydrate by sugars (mono- and disaccharides) in a high-fiber, low-saturated fat diet would affect indices of glucose tolerance. Diets differed in that the 50% of calories derived from carbohydrate was either 35% complex and 15% sugars (low-sugar) on 15% complex and 35% sugars (high-sugar). Summation of glucose responses 30-180 min following an oral glucose tolerance test was significantly higher in men, but not women, after they consumed the high-sugar diet. Corresponding insulin responses were significantly higher in men consuming the high-sugar compared to the low-sugar diet. Insulin binding was significantly lower during the base line period and after the high-sugar diet compared to the low-sugar diet. Results indicate that sugars adversely affect indices of glucose tolerance when they replace complex carbohydrates even in a high-fiber, low-saturated fat diet.
对10名男性和9名女性进行了研究，以确定在高纤维、低饱和脂肪饮食中用糖类（单糖和双糖）替代可利用的复合碳水化合物是否会影响葡萄糖耐量指标。饮食的不同之处在于，碳水化合物提供的50%热量中，要么是35%复合碳水化合物和15%糖类（低糖饮食），要么是15%复合碳水化合物和35%糖类（高糖饮食）。在口服葡萄糖耐量试验后30 - 180分钟的葡萄糖反应总和，男性在食用高糖饮食后显著升高，而女性则不然。与低糖饮食相比，食用高糖饮食的男性相应的胰岛素反应显著更高。与低糖饮食相比，在基线期和高糖饮食后胰岛素结合显著降低。结果表明，即使在高纤维、低饱和脂肪饮食中，当糖类替代复合碳水化合物时，也会对葡萄糖耐量指标产生不利影响。
