White Sarah E, Woolley Stephen D
Foundation Programme, Royal Liverpool University Hospital, Liverpool, UK.
Medical Microbiology Department, Liverpool Clinical Laboratories, Royal Liverpool University Hospital, Liverpool, UK.
Case Rep Infect Dis. 2018 Jun 20;2018:6708614. doi: 10.1155/2018/6708614. eCollection 2018.
This is a case of in the breast abscess of a penicillin-allergic woman. The mainstay of treatment for actinomycosis is penicillin, and there is a lack of literature describing nonpenicillin treatment options. A 69-year-old woman presented acutely with a breast abscess which was managed with incision and drainage and antibiotic therapy to good response. 21 days after presentation, were grown from the culture of pus, so the patient was recalled and more rigorous treatment and follow-up were initiated. The penicillin allergy led to difficulty in the identification of an appropriate antimicrobial agent that was also logistically feasible to be given on an outpatient IV basis. IV tigecycline followed by oral clarithromycin was found to be effective treatment.
这是一例青霉素过敏女性的乳腺脓肿病例。放线菌病的主要治疗药物是青霉素,而描述非青霉素治疗方案的文献较少。一名69岁女性因乳腺脓肿急性就诊,经切开引流和抗生素治疗后反应良好。就诊21天后,脓液培养长出[具体细菌名称未给出],因此召回患者并开始更严格的治疗和随访。青霉素过敏导致难以确定一种既合适又能在门诊进行静脉给药的可行抗菌药物。结果发现静脉用替加环素继以口服克拉霉素是有效的治疗方法。