Borka Katalin
II. Sz. Patológiai Intézet, Semmelweis Egyetem, Budapest, Hungary.
Magy Onkol. 2018 Jul 20;62(2):90-97. Epub 2018 Apr 3.
Tumors arising from the diffuse neuroendocrine (NE) system are mostly located in gastro-entero-pancreatic (GEP) tract and in the lung, and show increasing incidence and wide spectrum appearance. Different therapeutic possibilities need accurate diagnosis, classification and prognosis prediction, which determination for pathological diagnostics is a great challenge. All of these are based on the WHO classification, TNM classification of tumors of different location, and clinicopathological characterization. This review provides a comprehensive overview of the general characteristics of NE tumors, in particular the clinical-pathological properties of gastro-entero-pancreatic tumors and the requirements of correct pathological diagnosis for treatment.
起源于弥散神经内分泌（NE）系统的肿瘤大多位于胃肠胰（GEP）道和肺部，且发病率呈上升趋势，表现形式多样。不同的治疗方案需要准确的诊断、分类和预后预测，而病理诊断的确定是一项巨大挑战。所有这些都基于世界卫生组织（WHO）分类、不同部位肿瘤的TNM分类以及临床病理特征。本综述全面概述了神经内分泌肿瘤的一般特征，特别是胃肠胰肿瘤的临床病理特性以及正确病理诊断对治疗的要求。
