Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application, Department of Polymer Science and Engineering, State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China.
Soft Matter. 2018 Aug 1;14(30):6353-6359. doi: 10.1039/c8sm00909k.
C17H35CO-l-Val-l-Ala and C17H35CO-d-Val-d-Ala sodium salts can form physical gels in water, and self-assemble into right- and left-handed twisted nanoribbons, respectively. FT-IR and 1H NMR spectra indicate that the H-bonding between the neighboring valine residues and electrostatic interactions of carboxylate groups play important roles in the formation of helical nanoribbons. Circular dichroism characterization and theoretical chemical calculations indicate that the dipeptide segments pack in a helical manner. X-ray diffraction patterns and theoretical chemical simulations indicate an interdigitated bilayer structure. The hydrogels exhibit a thixotropic behavior. The twisted nanoribbons are able to align under directional force.
C17H35CO-l-Val-l-Ala 和 C17H35CO-d-Val-d-Ala 钠盐可以在水中形成物理凝胶，并分别自组装成右手和左手扭曲纳米带。FT-IR 和 1H NMR 谱表明，相邻缬氨酸残基之间的氢键和羧酸盐基团的静电相互作用在螺旋纳米带的形成中起重要作用。圆二色性表征和理论化学计算表明二肽段以螺旋方式堆积。X 射线衍射图谱和理论化学模拟表明存在交错双层结构。水凝胶表现出触变性。扭曲纳米带在定向力的作用下能够排列。
