Abdullin G Z
Fiziol Zh SSSR Im I M Sechenova. 1985 Nov;71(11):1329-38.
In chronic experiments on dogs, changes of adrenocorticotropic and glucocorticoid activities of blood plasma were studied under the effect of factors activating the hypothalamo-hypophyseal-adrenal system (morphine, electrical stimulation of the hypothalamus, surgical lesions). Similar as the general dynamics was, there was no complete analogy of the above two indices as the ACTH and cortisol (ACTH-activity and 17-OCS in some experiments) attain the maximal concentrations not always simultaneously, the character of changes can be opposite while in similar changes their intensity can be rather different. The data obtained disagree with the concept of exclusive dependence of the glucocorticoids secretion on the adenohypophysis. Apart from the adrenocorticotropic hormone, additional factors of extrahypophyseal origin seem to exist and affect the glucocorticoid response.
在对狗进行的慢性实验中，研究了激活下丘脑 - 垂体 - 肾上腺系统的因素（吗啡、下丘脑电刺激、手术损伤）作用下血浆促肾上腺皮质激素和糖皮质激素活性的变化。尽管总体动态相似，但上述两个指标（促肾上腺皮质激素和皮质醇，在某些实验中为促肾上腺皮质激素活性和17 - 氧皮质类固醇）并不完全相似，它们达到最大浓度并不总是同时发生，变化特征可能相反，而在相似变化中其强度可能差异很大。所获得的数据与糖皮质激素分泌完全依赖腺垂体的概念不一致。除促肾上腺皮质激素外，似乎还存在来自垂体外的其他因素影响糖皮质激素反应。
