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利用肺炎球菌和轮状病毒监测数据辅助疫苗决策:孟加拉国、亚美尼亚和冈比亚的一系列案例研究。

Using pneumococcal and rotavirus surveillance in vaccine decision-making: A series of case studies in Bangladesh, Armenia and the Gambia.

机构信息

Expanded Programme on Immunization (EPI), Department of Immunizations, Vaccines and Biologicals (IVB), World Health Organization, Geneva, Switzerland.

Child Health Research Foundation, Dhaka Shishu Hospital, Dhaka, Bangladesh.

出版信息

Vaccine. 2018 Aug 6;36(32 Pt B):4939-4943. doi: 10.1016/j.vaccine.2018.06.001. Epub 2018 Jun 29.

DOI:10.1016/j.vaccine.2018.06.001
PMID:30037484
Abstract

Pneumonia and diarrhea are the leading causes of child morbidity and mortality globally and are vaccine preventable. The WHO-coordinated Global Rotavirus and Invasive Bacterial Vaccine-Preventable Disease Surveillance Networks support surveillance systems across WHO regions to provide burden of disease data for countries to make evidence-based decisions about introducing vaccines and to demonstrate the impact of vaccines on disease burden. These surveillance networks help fill the gaps in data in low and middle-income countries where disease burden and risk are high but support to sustain surveillance activities and generate data is low. Through a series of country case studies, this paper reviews the successful use of surveillance data for disease caused by pneumococcus and rotavirus in informing national vaccine policy in Bangladesh, Armenia and The Gambia. The case studies delve into ways in which countries are leveraging and building capacity in existing surveillance infrastructure to monitor other diseases of concern in the country. Local institutions have been identified to play a critical role in making surveillance data available to policymakers. We recommend that countries review local or regional surveillance data in making vaccine policy decisions. Documenting use of surveillance activities can be used as advocacy tools to convince governments and external funders to invest in surveillance and make it a priority immunization activity.

摘要

肺炎和腹泻是导致全球儿童发病和死亡的主要原因,可通过疫苗预防。世卫组织协调的全球轮状病毒和侵袭性细菌性疾病疫苗可预防疾病监测网络支持在世卫组织各区域的监测系统,为各国提供疾病负担数据,以便各国能够根据证据做出引入疫苗的决策,并展示疫苗对疾病负担的影响。这些监测网络有助于填补中低收入国家数据空白,这些国家疾病负担和风险高,但支持维持监测活动和生成数据的资源却很少。本文通过一系列国家案例研究,审查了利用肺炎球菌和轮状病毒疾病监测数据为孟加拉国、亚美尼亚和冈比亚的国家疫苗政策提供信息的成功经验。这些案例研究深入探讨了各国如何利用和建立现有监测基础设施的能力,以监测该国其他相关疾病。已经确定了地方机构在向决策者提供监测数据方面发挥关键作用。我们建议各国在制定疫苗政策决定时审查当地或区域监测数据。记录监测活动的使用情况可以作为宣传工具,说服政府和外部供资者投资于监测工作,并将其作为免疫接种的重点活动。

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