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Relationship between clostridium difficile infection and gastrointestinal graft versus host disease in recipients of allogeneic stem cell transplantation.异基因干细胞移植受者中艰难梭菌感染与胃肠道移植物抗宿主病的关系
Bone Marrow Transplant. 2019 Jan;54(1):164-167. doi: 10.1038/s41409-018-0270-x. Epub 2018 Jul 23.
2
Changing epidemiology of Clostridium difficile-associated disease during stem cell transplantation.造血干细胞移植后艰难梭菌相关性疾病的流行病学变化。
Biol Blood Marrow Transplant. 2013 Mar;19(3):405-9. doi: 10.1016/j.bbmt.2012.10.030. Epub 2012 Dec 4.
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Recurrence of Clostridium difficile infection after total colectomy in an allogeneic stem cell transplant patient.一名异基因干细胞移植患者全结肠切除术后艰难梭菌感染复发
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Late Gastrointestinal Complications of Allogeneic Hematopoietic Stem Cell Transplantation in Adults.成人异基因造血干细胞移植的晚期胃肠道并发症。
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Clostridium difficile infection in allogeneic stem cell transplant recipients is associated with severe graft-versus-host disease and non-relapse mortality.异基因造血干细胞移植受者的艰难梭菌感染与严重移植物抗宿主病及非复发死亡率相关。
Bone Marrow Transplant. 2000 Oct;26(8):871-6. doi: 10.1038/sj.bmt.1702627.
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Upper gastrointestinal acute graft--host disease adds minimal prognostic value in isolation or with other graft--host disease symptoms as currently diagnosed and treated.上消化道急性移植物抗宿主病在目前的诊断和治疗中，单独或与其他移植物抗宿主病症状一起，增加的预后价值极小。
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Interleukin-22 levels are increased in gastrointestinal graft--host disease in children.儿童胃肠道移植物抗宿主病中白细胞介素-22水平升高。
Haematologica. 2018 Oct;103(10):e480-e482. doi: 10.3324/haematol.2017.174771. Epub 2018 May 17.
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Role of the intestinal mucosa in acute gastrointestinal GVHD.肠道黏膜在急性胃肠道移植物抗宿主病中的作用。
Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):119-127. doi: 10.1182/asheducation-2016.1.119.
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[Intestinal microbiota and allogeneic stem cell transplantation].[肠道微生物群与异基因干细胞移植]
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Outcome of gastrointestinal graft-versus-host disease according to the treatment response.根据治疗反应评估胃肠道移植物抗宿主病的结局。
Ann Hematol. 2018 Oct;97(10):1951-1960. doi: 10.1007/s00277-018-3385-7. Epub 2018 Jun 2.

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Reduction of product composition variability using pooled microbiome ecosystem therapy and consequence in two infectious murine models.利用 pooled 微生物组生态疗法降低产品成分变异性及其在两种感染性啮齿动物模型中的结果。
Appl Environ Microbiol. 2024 May 21;90(5):e0001624. doi: 10.1128/aem.00016-24. Epub 2024 Apr 23.
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Effective treatment of Clostridioides difficile infection improves survival and affects graft-versus-host disease: a multicenter study by the Polish Adult Leukemia Group.艰难梭菌感染的有效治疗可提高生存率并影响移植物抗宿主病：波兰成人白血病组的一项多中心研究。
Sci Rep. 2024 Mar 11;14(1):5947. doi: 10.1038/s41598-024-56336-3.
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Non-viral pathogens of infectious diarrhoea post-allogeneic stem cell transplantation are associated with graft-versus-host disease.异基因造血干细胞移植后感染性腹泻的非病毒性病原体与移植物抗宿主病有关。
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The incidence and impact of clostridioides difficile infection on transplant outcomes in acute leukemia and MDS after allogeneic hematopoietic cell transplant-a CIBMTR study.异基因造血细胞移植后急性白血病和 MDS 中艰难梭菌感染的发生率和影响：CIBMTR 研究。
Bone Marrow Transplant. 2023 Apr;58(4):360-366. doi: 10.1038/s41409-022-01896-z. Epub 2022 Dec 21.
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Prevalence of Infection in the Hematopoietic Transplantation Setting: Update of Systematic Review and Meta-Analysis.造血移植环境中的感染发生率：系统评价和荟萃分析更新。
Front Cell Infect Microbiol. 2022 Feb 21;12:801475. doi: 10.3389/fcimb.2022.801475. eCollection 2022.
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Make Sure You Have a Safety Net: Updates in the Prevention and Management of Infectious Complications in Stem Cell Transplant Recipients.确保你有一个安全保障：干细胞移植受者感染性并发症预防与管理的最新进展
J Clin Med. 2020 Mar 21;9(3):865. doi: 10.3390/jcm9030865.

本文引用的文献

1
The intestinal microbiota in allogeneic hematopoietic cell transplant and graft-versus-host disease.异基因造血细胞移植与移植物抗宿主病中的肠道微生物群
Blood. 2017 Feb 23;129(8):927-933. doi: 10.1182/blood-2016-09-691394. Epub 2016 Dec 9.
2
Clostridium Difficile Colonization in Hematopoietic Stem Cell Transplant Recipients: A Prospective Study of the Epidemiology and Outcomes Involving Toxigenic and Nontoxigenic Strains.造血干细胞移植受者艰难梭菌定植：一项关于产毒菌株和非产毒菌株的流行病学及结局的前瞻性研究。
Biol Blood Marrow Transplant. 2016 Jan;22(1):157-63. doi: 10.1016/j.bbmt.2015.07.020. Epub 2015 Jul 26.
3
Low-dose antithymocyte globulin enhanced the efficacy of tacrolimus and mycophenolate for GVHD prophylaxis in recipients of unrelated SCT.低剂量抗胸腺细胞球蛋白增强了他克莫司和霉酚酸酯在无关供者造血干细胞移植受者中预防移植物抗宿主病的疗效。
Bone Marrow Transplant. 2015 Jan;50(1):106-12. doi: 10.1038/bmt.2014.203. Epub 2014 Oct 6.
4
Clostridium difficile infection in the hematopoietic unit: a meta-analysis of published studies.造血单元中的艰难梭菌感染：已发表研究的荟萃分析
Biol Blood Marrow Transplant. 2014 Oct;20(10):1650-4. doi: 10.1016/j.bbmt.2014.06.001. Epub 2014 Jun 7.
5
Relative incidences and outcomes of Clostridium difficile infection following transplantation of unrelated cord blood, unrelated bone marrow, and related peripheral blood in adult patients: a single institute study.成人患者中无关脐血、无关骨髓和相关外周血移植后艰难梭菌感染的相对发病率及转归：一项单机构研究
Transpl Infect Dis. 2014 Jun;16(3):412-20. doi: 10.1111/tid.12224. Epub 2014 May 9.
6
Intestinal dysbiosis and depletion of butyrogenic bacteria in Clostridium difficile infection and nosocomial diarrhea.艰难梭菌感染和医院获得性腹泻中的肠道菌群失调和产丁酸菌减少。
J Clin Microbiol. 2013 Sep;51(9):2884-92. doi: 10.1128/JCM.00845-13. Epub 2013 Jun 26.
7
Epidemiology and outcomes of Clostridium difficile infections in hematopoietic stem cell transplant recipients.造血干细胞移植受者艰难梭菌感染的流行病学和结局。
Clin Infect Dis. 2012 Apr;54(8):1053-63. doi: 10.1093/cid/cir1035. Epub 2012 Mar 12.
8
Recent epidemiology of Clostridium difficile infection during hematopoietic stem cell transplantation.造血干细胞移植期间艰难梭菌感染的最新流行病学。
Clin Transplant. 2011 Jan-Feb;25(1):E82-7. doi: 10.1111/j.1399-0012.2010.01331.x. Epub 2010 Oct 25.
9
Mechanisms of action of antithymocyte globulin: T-cell depletion and beyond.抗胸腺细胞球蛋白的作用机制：T细胞清除及其他作用
Leukemia. 2007 Jul;21(7):1387-94. doi: 10.1038/sj.leu.2404683. Epub 2007 Apr 5.
10
Acute graft-versus-host disease: pathophysiology, clinical manifestations, and management.急性移植物抗宿主病：病理生理学、临床表现及管理
Cancer. 2004 Nov 1;101(9):1936-46. doi: 10.1002/cncr.20613.

Relationship between clostridium difficile infection and gastrointestinal graft versus host disease in recipients of allogeneic stem cell transplantation.

作者信息

Bhutani Divaya, Jaiyeoba Charles, Kim Seongho, Naylor Paul, Uberti Joseph P, Ratanatharathorn Voravit, Ayash Lois, Deol Abhinav, Alavi Asif, Revankar Sanjay, Chandrasekar Pranatharthi

机构信息

Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.

Department of Internal medicine, Wayne State University, Detroit, MI, USA.

出版信息

Bone Marrow Transplant. 2019 Jan;54(1):164-167. doi: 10.1038/s41409-018-0270-x. Epub 2018 Jul 23.

DOI:10.1038/s41409-018-0270-x
PMID:30038352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6844071/
Abstract
摘要