Weller I V
Scand J Gastroenterol Suppl. 1985;114:77-89. doi: 10.3109/00365528509093769.
The epidemiological, immunological and early virological observations on the acquired immune deficiency syndrome (AIDS) suggested that an agent was involved which was sexually, parenterally and perinatally transmitted and perhaps tropic for T helper lymphocytes. A new subgroup of human T lymphotropic retroviruses have been identified ans seroepidemiological studies suggest that they are aetiologically related to AIDS. The syndrome is characterised by the development of tumors: such as Kaposi's sarcoma and non-Hodgkins lymphoma, with an aggressive clinical course and infection by a wide spectrum of opportunistic organisms. Both the tumours and the infections commonly involve the gut.
对获得性免疫缺陷综合征(艾滋病)的流行病学、免疫学及早期病毒学观察表明,有一种病原体参与其中,它可通过性传播、肠道外传播及母婴传播,并且可能对辅助性T淋巴细胞具有嗜性。现已鉴定出一种人类嗜T淋巴细胞逆转录病毒的新亚群,血清流行病学研究表明,它们在病因上与艾滋病相关。该综合征的特征是出现肿瘤,如卡波西肉瘤和非霍奇金淋巴瘤,临床病程凶险,还会受到多种机会性生物体的感染。肿瘤和感染通常都累及肠道。