腹泻的获得性免疫缺陷综合征患者中急性肠道病毒病原体的患病率。
Prevalence of acute enteric viral pathogens in acquired immunodeficiency syndrome patients with diarrhea.
作者信息
Kaljot K T, Ling J P, Gold J W, Laughon B E, Bartlett J G, Kotler D P, Oshiro L S, Greenberg H B
机构信息
Division of Gastroenterology, Stanford University School of Medicine, California.
出版信息
Gastroenterology. 1989 Oct;97(4):1031-2. doi: 10.1016/0016-5085(89)91516-3.
Abstract
Diarrhea due to enteric pathogens is an important complication of advanced human immunodeficiency virus infection. Whereas numerous bacterial and parasitic agents have been implicated, the role of pathogenic enteric viruses is less clear. Stools from 153 human immunodeficiency virus seropositive men were tested by electrophoresis, enzyme-linked immunosorbent assay, and immune electron microscopy for the presence of rotaviruses (group A and non-group A), adenoviruses, and Norwalk agent. Virus was detected in 9% of the patients with acquired immunodeficiency syndrome, 3% of the patients with acquired immunodeficiency syndrome-related complex, and none of the seropositive men without these diagnoses. Virus detection was not more likely in stool from patients with diarrhea.
摘要
肠道病原体引起的腹泻是晚期人类免疫缺陷病毒感染的重要并发症。虽然已发现许多细菌和寄生虫病原体，但致病性肠道病毒的作用尚不清楚。通过电泳、酶联免疫吸附测定和免疫电子显微镜对153名人类免疫缺陷病毒血清阳性男性的粪便进行检测，以确定是否存在轮状病毒（A组和非A组）、腺病毒和诺沃克病毒。在9%的获得性免疫缺陷综合征患者、3%的获得性免疫缺陷综合征相关综合征患者的粪便中检测到病毒，而在无上述诊断的血清阳性男性中未检测到病毒。腹泻患者的粪便中病毒检测阳性的可能性并不更高。
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