白内障手术中用于治疗糖尿病性黄斑水肿时，球后注射与玻璃体内注射曲安奈德疗效的比较。
Comparison of the Efficacy of Sub-Tenon versus Intravitreal Triamcinolone Acetonide Injection during Cataract Surgery for Diabetic Macular Edema.
作者信息
Tatsumi Tomoaki, Oshitari Toshiyuki, Ando Takaaki, Takatsuna Yoko, Arai Miyuki, Baba Takayuki, Sato Eiju, Yamamoto Shuichi
出版信息
Ophthalmologica. 2019;241(1):17-23. doi: 10.1159/000489716. Epub 2018 Jul 24.
PURPOSE
We compared the efficacy of sub-Tenon triamcinolone acetonide (STTA) to intravitreal triamcinolone aceto-nide (IVTA) injections during cataract surgery (CS) for patients with diabetic macular edema (DME).
METHODS
The medical records of 33 eyes (26 patients) with DME which had undergone CS with STTA were compared to those of 34 eyes (27 patients) with DME which had undergone CS with IVTA. Central foveal thickness and best-corrected visual acuity (BCVA) were measured at the baseline and 1, 3, and 6 months after the surgery.
RESULTS
The BCVAs after STTA and IVTA were significantly improved at 3 and 6 months. Thirteen eyes in the IVTA group and 21 eyes in the STTA group required other therapies (p < 0.05). One case developed intraocular pressure elevation after IVTA and underwent selective la ser trabeculoplasty.
CONCLUSIONS
Ophthalmologists should consider the merits and demerits of IVTA and STTA for DME treatment after CS.
目的
我们比较了在白内障手术（CS）期间，对于糖尿病性黄斑水肿（DME）患者，球周注射曲安奈德（STTA）与玻璃体内注射曲安奈德（IVTA）的疗效。
方法
将33只眼（26例患者）接受CS联合STTA治疗的DME患者的病历与34只眼（27例患者）接受CS联合IVTA治疗的DME患者的病历进行比较。在基线以及术后1、3和6个月测量中心凹厚度和最佳矫正视力（BCVA）。
结果
STTA和IVTA治疗后3个月和6个月时BCVA均显著改善。IVTA组13只眼和STTA组21只眼需要其他治疗（p<0.05）。1例患者在IVTA治疗后出现眼压升高并接受了选择性激光小梁成形术。
结论
眼科医生在CS后治疗DME时应考虑IVTA和STTA的优缺点。
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