Calicó I, Moraga Llop F A, Español T, Bertrán Sangués J M, Fernández Pérez F
An Esp Pediatr. 1985 Nov 15;23(6):403-11.
We report 27 children with respiratory tract disease in whom cytomegalovirus was isolated. These group excludes transplant patients and those on hemodialysis and mononucleosis. At the time of virus studies 7 had pneumonia, 3 chronic bronchopneumopathy, 2 bronchopneumonia, 8 pertussoid syndrome, 6 bronchitis or bronchiolitis and 1 laryngitis with glottic oedema. Virus studies consisted in cell cultures of biological products (pharyngeal exudates and urine). They were positive in 18 pharyngeal exudates, 24 urines, 2 bronchial brushings and 1 bronchoaspiration. In only 5 patients a complete serologic study was performed, with 3 seroconversions and one case of persistent high titers. Three patients had severe immune disease (2 hipogammaglobulinemias) and 1 dysgammaglobulinemia. These findings are discussed.
我们报告了27例分离出巨细胞病毒的呼吸道疾病患儿。这组病例不包括移植患者、接受血液透析的患者和单核细胞增多症患者。在进行病毒研究时,7例患有肺炎,3例患有慢性支气管肺炎,2例患有支气管肺炎,8例患有百日咳样综合征,6例患有支气管炎或细支气管炎,1例患有伴有声门水肿的喉炎。病毒研究包括生物制品(咽部分泌物和尿液)的细胞培养。18例咽部分泌物、24例尿液、2例支气管刷检物和1例支气管吸出物检测呈阳性。仅对5例患者进行了完整的血清学研究,其中3例出现血清转化,1例持续高滴度。3例患者患有严重免疫疾病(2例低丙种球蛋白血症)和1例异常丙种球蛋白血症。对这些发现进行了讨论。