[基于三维立体摄影测量法的A型肉毒毒素治疗咬肌肥大疗效观察的定量分析]

[Quantitative analysis based on three-dimensional stereophotogrammetry in the observation of curative effect of botulinum toxin A on masseter hypertrophy].

作者信息

Xue Zihan, Zeng Wei, Chen Zhaoyang, Han Yan

出版信息

Zhonghua Zheng Xing Wai Ke Za Zhi. 2016 Jul;32(4):272-5.

Abstract

OBJECTIVE

To observe the curative effect of botulinum toxin A on masseter hypertrophy using three-dimensional stereophotogrammetry.

METHODS

46 cases with masseter hypertrophy (92 masseters) who received botulinum toxin A injection were enrolled from May 2013 to August 2014.Data were collected before and 3,6 and 9 months after injection.

RESULTS

The efficacy of botulinum toxin A in reducing the volume of the lower face has been proven by MAS 3D.3 and 6 months after injection, the volume reduction were measured as 7.23 ％,2.15％ respectively (P ＜ 0.05).The coefficients between middle and lower thirds of the face showed an increase compatible with thinning of the lower face with statistical significance at 3 months follow up. The increase percentage was measured by MAS 3D as 40.21％ between pre-and post-injection (P ＜ 0.05),and the increase percentage was 21.03％ at 6 months follow up (P ＜ 0.05).While 9 months after injection,the value was insignificant comparing to pretreatment at 9 months.

CONCLUSIONS

Three-dimensional stereophotogrammetry provides a safe effective and direct way to observe masseter hypertrophy.

摘要

目的

采用三维立体摄影测量法观察A型肉毒毒素治疗咬肌肥大的疗效。

方法

选取2013年5月至2014年8月期间接受A型肉毒毒素注射治疗的咬肌肥大患者46例（92侧咬肌）。在注射前及注射后3、6、9个月收集数据。

结果

三维立体摄影测量法（MAS 3D）证实了A型肉毒毒素在减小下面部体积方面的疗效。注射后3个月和6个月，体积减小率分别为7.23％、2.15％（P＜0.05）。面部中下三分之一之间的系数增加，与下面部变薄相符，在随访3个月时有统计学意义。三维立体摄影测量法（MAS 3D）测得注射前后增加百分比为40.21％（P＜0.05），随访6个月时增加百分比为21.03％（P＜0.05）。而注射后9个月，与9个月时的治疗前值相比无显著差异。