Zyluk Andrzej, Puchalski Piotr
Pomeranian Medical University, Department of General and Hand Surgery.
Handchir Mikrochir Plast Chir. 2018 Jun;50(3):190-195. doi: 10.1055/a-0641-5762. Epub 2018 Jul 25.
We report on the outcomes of treatment for severe pain associated with long-standing, refractory CRPS in 10 female patients by continuous brachial plexus analgesia. The duration of the disease prior to treatment was 3.5 years on average, and mean baseline pain intensity was 8.3 on a numeric analogue scale (NRS). All patients met the Budapest criteria for the diagnosis of CRPS. A spinal catheter was implanted into the brachial plexus via an open axillary approach.
Each patient underwent a mean of 4.4 (range 2-8) spinal catheter implantations. A rapid and strong analgesic effect was observed immediately after the injection of bupivacaine solution was started: Pain decreased from a mean of 8.3 to 1.6. The duration of maintaining the catheter in the brachial plexus and achieving effective analgesia was 5.3 months (range 2-12). After the removal of the catheter, the pain returned to baseline. No patient achieved a permanent, or at least partial, reduction of pain after completing this therapy.
我们报告了通过连续臂丛神经镇痛治疗10例患有长期难治性复杂性区域疼痛综合征(CRPS)的女性患者严重疼痛的治疗结果。治疗前疾病持续时间平均为3.5年,数字评分量表(NRS)上的平均基线疼痛强度为8.3。所有患者均符合CRPS诊断的布达佩斯标准。通过开放腋窝入路将脊髓导管植入臂丛神经。
每位患者平均接受4.4次(范围2 - 8次)脊髓导管植入。开始注射布比卡因溶液后立即观察到快速且强烈的镇痛效果:疼痛从平均8.3降至1.6。将导管保留在臂丛神经中并实现有效镇痛的持续时间为5.3个月(范围2 - 12个月)。拔除导管后,疼痛恢复至基线水平。完成该治疗后,没有患者实现疼痛的永久性或至少部分减轻。