Ellis M E, Tayoub F
Br J Dis Chest. 1986 Jan;80(1):7-12. doi: 10.1016/0007-0971(86)90003-3.
In a study of 41 African Zulus with acute pulmonary tuberculosis, 55% were found to have a suboptimal cortisol response to Synacthen and all had very low plasma dehydroepiandrosterone levels. Following a 2-week course of antituberculous chemotherapy there was an improvement in adrenal corticosteroid function with a reduction to 30% of those showing an impaired cortisol response to Synacthen, but adrenal androgen function did not improve in any. Patients who received rifampicin as part of their treatment appeared to show less improvement in adrenal corticosteroid function when compared to a group who received antituberculous treatment which did not include rifampicin.
在一项针对41名患有急性肺结核的非洲祖鲁人的研究中，发现55%的人对合成促肾上腺皮质激素的皮质醇反应欠佳，且所有人的血浆脱氢表雄酮水平都非常低。经过为期2周的抗结核化疗后，肾上腺皮质类固醇功能有所改善，对合成促肾上腺皮质激素皮质醇反应受损的比例降至30%，但肾上腺雄激素功能均未改善。与接受不包括利福平的抗结核治疗的组相比，接受利福平作为治疗一部分的患者肾上腺皮质类固醇功能的改善似乎较少。
