肿瘤门诊老年癌症患者潜在不适当用药情况的评估
Evaluation of potentially inappropriate medication utilization in elderly patients with cancer at outpatient oncology unit.
作者信息
Paksoy Ceylan, Özkan Öznur, Ustaalioğlu Bala Bö, Sancar Mesut, Demirtunç Refik, Izzettin Fikret V, Okuyan Betul
机构信息
1 Department of Clinical Pharmacy, Marmara University Faculty of Pharmacy, Istanbul, Turkey.
2 Department of Medical Oncology, Health Science University, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey.
出版信息
J Oncol Pharm Pract. 2019 Sep;25(6):1321-1327. doi: 10.1177/1078155218788698. Epub 2018 Jul 25.
BACKGROUND
The aim of the study was to evaluate potentially inappropriate medication use in elderly patients with cancer.
METHOD
This study was conducted at outpatient oncology clinic from December 2014 to March 2015 among elderly cancer patients. Screening Tool of Older Person's Prescriptions/Screening Tool to Alert doctors to Right Treatment criteria were used to identify potentially inappropriate medication in elderly patients.
RESULTS
Among 114 cancer patients 55.26% of them were male and the mean age of them was 71.78 ± 5.50 (years). The most common concurrent diseases were hypertension in 45 (39.47%) and diabetes in 26 (22.81%) patients. Polypharmacy (≥5 medications) was seen in 94.73% of them. Eighteen patients (15.79%) utilized medications inappropriately according to Screening Tool of Older Person's Prescriptions criteria. Medication omissions were identified in 112 patients (98.25%) with Screening Tool to Alert doctors to Right Treatment criteria.
CONCLUSIONS
Clinical pharmacists could improve the current prescribing practices in elderly patients with cancer by assessing potentially inappropriate medications.
背景
本研究的目的是评估老年癌症患者中潜在不适当用药情况。
方法
本研究于2014年12月至2015年3月在门诊肿瘤诊所对老年癌症患者进行。使用老年人处方筛查工具/提醒医生正确治疗标准的筛查工具来识别老年患者中潜在不适当的药物。
结果
114例癌症患者中，55.26%为男性，平均年龄为71.78±5.50（岁）。最常见的并发疾病是45例（39.47%）高血压和26例（22.81%）糖尿病患者。94.73%的患者存在多重用药（≥5种药物）。根据老年人处方筛查工具标准，18例患者（15.79%）用药不当。根据提醒医生正确治疗标准的筛查工具，112例患者（98.25%）存在用药遗漏。
结论
临床药师可通过评估潜在不适当药物来改善老年癌症患者当前的处方实践。
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