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对青少年人群使用大麻的简短干预措施:系统评价、荟萃分析和证据图谱的研究方案。

Brief interventions for cannabis use in emerging adults: protocol for a systematic review, meta-analysis, and evidence map.

机构信息

Department of Health Research, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.

Michael G. De Groote Centre for Medicinal Cannabis Research, McMaster University/St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.

出版信息

Syst Rev. 2018 Jul 25;7(1):106. doi: 10.1186/s13643-018-0772-z.

Abstract

BACKGROUND

Rates of cannabis use are highest during emerging adulthood (age 18-25), with the prevalence of near daily and daily increasing among this age group. Emerging adults are clinically challenging in terms of harmful cannabis use due to perceptions of high rates of peer use, social acceptance, and low risk of harm. Brief interventions to increase awareness and promote motivation to change are therefore particularly important for this age group. There is existing evidence on the effectiveness of brief interventions for alcohol in emerging adults, but it is not clear if comparable evidence is present for cannabis. The objective of this systematic review is to summarize and critically appraise the existing literature of brief interventions for cannabis use both narratively, to describe the content and delivery of existing interventions, and meta-analytically, to determine the aggregated efficacy of these interventions on cannabis use and other outcomes (e.g., other substance use, mental health, help-seeking behaviors, and academic and occupational outcomes).

METHODS

A systematic search of randomized controlled trials, quasi-experimental trials, and pre-post designs will be conducted in the following electronic databases: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine, Cumulative Index to Nursing and Allied Health Literature, and PsycINFO. Ongoing trials will be identified using the World Health Organization International Clinical Trials Registry Platform, ClinicalTrials.gov , and Current Controlled Trials. Unpublished trials will be identified using Proquest Dissertations, OpenGrey, Google Scholar, and brief interventions on the Substance Abuse and Mental Health Services Administration webpage. Two authors will independently screen and extract data from articles using a predetermined screening and extraction forms (which will include risk of bias assessments). Calibration exercises will be performed prior to full screening and extraction. Disagreements will be resolved through discussion or consultation with a third reviewer. All studies will be reported narratively, and if appropriate, we will perform random effects meta-analyses with subgroup analyses and meta-regression.

DISCUSSION

Results of this review are expected to provide guidance on the content, delivery methods, and effectiveness of brief interventions for cannabis use to assist post-secondary institutions in identifying brief intervention strategies to implement prior to or in response to legalization.

SYSTEMATIC REVIEW REGISTRATION

CRD42018085412.

摘要

背景

大麻使用率在成年早期(18-25 岁)最高,该年龄段的近日常用和每日使用率都在增加。由于同龄人使用率高、社会接受度高以及危害风险低,成年早期人群在大麻的有害使用方面存在临床挑战。因此,提高认识和促进改变意愿的简短干预措施对这一年龄段尤为重要。已经有关于简短干预措施对成年早期人群中酒精使用效果的证据,但对于大麻使用,是否存在类似的证据尚不清楚。本系统评价的目的是综述和批判性评估简短干预措施治疗大麻使用的现有文献,既进行叙述性总结以描述现有干预措施的内容和实施方式,也进行荟萃分析以确定这些干预措施对大麻使用和其他结果(例如其他物质使用、心理健康、寻求帮助的行为以及学术和职业结果)的综合效果。

方法

将对随机对照试验、准实验试验和前后设计进行系统检索,检索范围包括以下电子数据库:MEDLINE、EMBASE、Cochrane 对照试验中心注册库、辅助和补充医学、护理学和联合健康文献累积索引、以及 PsycINFO。将通过世界卫生组织国际临床试验注册平台、ClinicalTrials.gov 和当前对照试验来识别正在进行的试验。将通过 Proquest Dissertations、OpenGrey、Google Scholar 以及物质滥用和心理健康服务管理局网页上的简短干预措施来识别未发表的试验。两位作者将使用预定的筛选和提取表格(其中将包括偏倚风险评估)独立筛选和提取文章中的数据。在全面筛选和提取之前,将进行校准练习。分歧将通过讨论或咨询第三位评审员来解决。所有研究都将进行叙述性报告,如果适当,我们将进行随机效应荟萃分析,包括亚组分析和荟萃回归。

讨论

预计本综述的结果将为大麻使用简短干预措施的内容、实施方法和有效性提供指导,以帮助大专院校在大麻合法化之前或之后确定实施简短干预措施的策略。

系统评价注册

CRD42018085412。

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